Thymosin Alpha-1 10mg - 79 € | Lab Peptides France

Name: Thymosin Alpha-1
Brand: Lab Peptides France
SKU: thymosin-alpha-1-10mg
Price: 79.00 EUR
Availability: InStock

Zoom

5mg47,00 €10mg79,00 €

79,00 €

Impuestos incluidos • Entrega gratis desde 99€

+3,95 € en cashback de fidelidad, con una cuenta. Crear mi cuenta

18 en stock, listo para enviar

Prochain départ : samedi 3 octobre

Stock en Francia

Suscripción

71,10 €-10 %en lugar de 79,00 €

-10 % de por vida en cada cicloPause, salte o cancele en 1 clicSin compromiso, sin gastos ocultos

Tu kit completo

Vial 10mgIncluido
Agua bacteriostáticaAñadir
Jeringas de 1 mlAñadir

El vial por sí solo no puede usarse tal cual. Un vial sellado de Thymosin Alpha-1 10mg, liofilizado, sin etiquetado individual.

No olvide lo imprescindible

Eau Bactériostatique

7,90 €

Seringue de précision 1ml 29Gx107,90 €

Lingettes alcool isopropylique 70%x103,90 €

Se compran juntos a menudo

Cagrilintide 5mg35,00 €

DSIP 5mg34,00 €

MOTS-c 10mg32,00 €

CJC-1295 NO DAC 10mg49,00 €

Thymosin Alpha-1 10mg (Talpha1, thymalfasin) is an N-acetylated 28 amino acid polypeptide, the bioactive fragment of thymosin fraction 5 secreted by the thymus. Identified in the 1970s by Allan Goldstein's team, it is today the most studied thymic peptide in the immunology literature, to the point of having yielded a drug marketed as Zadaxin in over thirty countries as a reference immunomodulator.

This 10mg format is the reinforced format: it doubles the material of the standard 5mg vial, sized for demanding immunological research protocols or extended fractionated-dose explorations, without multiplying reconstitutions. A single HPLC >98% controlled batch to run a complete series of experiments with homogeneous material.

Unlike growth or tissue-repair peptides, Thymosin Alpha-1 targets a single system with remarkable precision: cellular immunity. It is the reference tool for studying T lymphocyte maturation, Th1/Th2 balance and dendritic cell response, making it a must-have in immunomodulation protocols and seasonal immune-stress models.

Science

01
Mecanismo de acción

Thymosin Alpha-1's mechanism of action relies on a coordinated activation of innate and adaptive immunity, which sets it apart from single-target immunostimulants.

Toll-like receptor activation. Talpha1 activates the TLR-2 and TLR-9 receptors on the surface of dendritic cells and monocytes. This binding triggers the MyD88 pathway then NF-kappaB translocation, leading to dendritic cell maturation and enhanced antigen presentation. It is the initiating event of the immunomodulatory cascade.

Th1 orientation and T lymphocyte maturation. Talpha1 promotes the differentiation of helper T lymphocytes toward the Th1 profile, with increased production of IL-2 and interferon gamma. It stimulates T lymphocyte maturation within the thymus, increases functional CD4+ and CD8+ populations and restores a favorable Th1/Th2 ratio in documented immunosuppression contexts.

NK activity and rebalancing. Beyond T lymphocytes, Talpha1 increases the cytotoxic activity of NK (natural killer) cells and modulates the production of pro- and anti-inflammatory cytokines, tending to rebalance a dysregulated immune system rather than over-stimulate it. This bidirectional modulation property is the peptide's pharmacological signature and explains its adjuvant use in varied clinical contexts.

Clinical data

02Estudios clínicos

Thymosin Alpha-1 has an exceptional clinical corpus for a peptide, accumulated over more than three decades.

Chronic viral hepatitis. This is thymalfasin's (Zadaxin) historical indication: numerous trials on chronic hepatitis B and C show improved virological response, alone or in combination with interferons, founding its approval in over thirty countries.

Vaccine adjuvant in the elderly. Several studies document an improved vaccine response (influenza, hepatitis B) in populations with weakened immunity, notably elderly subjects and hemodialysis patients, with increased post-vaccination antibody titers.

Sepsis and critical care. Clinical trials on severe sepsis (including Chinese multicenter studies) evaluated Talpha1 as a modulator of the immune response in immunoparalysis states, with signals on the restoration of lymphocyte populations.

Adjuvant oncology and recent data. The literature explores Talpha1 as a chemotherapy adjuvant (lymphocyte recovery, quality of life) and, more recently, its value in lymphocyte-exhaustion contexts of severe viral infections, where restoration of T lymphocyte counts has been observed.

These data, though numerous, retain methodological heterogeneity. Atlas Lab Thymosin Alpha-1 remains a research tool, without therapeutic status in the context of its sale.

Todavía no hay referencias para este péptido: busque en PubMed la literatura científica asociada.

Los estudios enumerados se facilitan únicamente con fines documentales y de investigación. No constituyen una indicación terapéutica ni una recomendación de uso humano. Este producto es estrictamente de uso exclusivo en laboratorio (RUO).

Lab workflow

03
Protocolos de investigación

The Atlas Lab Thymosin Alpha-1 10mg vial is reconstituted with bacteriostatic water. For a comfortable working concentration, 2 ml of bacteriostatic water yields 5 mg/ml; 1 ml yields 10 mg/ml for protocols requiring a small draw volume. The 10mg format allows long series without opening a new batch.

Reference schemes. The thymalfasin literature classically uses repeated subcutaneous administrations, often twice weekly over several weeks in immunomodulation protocols, or daily in the acute phase of immune-stress models. Talpha1's half-life (about 2 hours) explains the use of regular administrations rather than a single dose. Precise fractioning depends on the research model.

Handling. Reconstitute gently, without vortexing, letting the solvent glide down the wall. The 28 amino acid sequence is more sensitive than short peptides: avoid heat and mechanical agitation, draw under aseptic conditions, and maintain the cold chain after reconstitution.

Parameters provided for in vitro and model research documentation. For research use only (RUO), no human, diagnostic or therapeutic use.

Reconstitución para este formato (10 mg)Volúmenes estándar utilizados en laboratorio

Agua añadida	Concentración	Marca de lectura
1 ml	10 mg/ml	10 UI = 1 mg
2 ml	5 mg/ml	40 UI = 2 mg

El volumen de agua no cambia el producto, solo su concentración. Introduzca el agua despacio por la pared del vial, nunca directamente sobre el liofilizado, y luego gírelo suavemente sin agitar. Las marcas se dan sobre una jeringa de 1 ml graduada en 100 unidades.

Asepsia

Desinfecte las superficies y los tapones (alcohol al 70%).

Disolvente

Extraiga el volumen necesario de agua bacteriostática.

Introducción

Inyecte suavemente contra la pared del vial (evite el chorro directo sobre el polvo).

Solubilización

Haga rodar el vial suavemente. No lo agite con fuerza (riesgo de degradación).

Conservación de la soluciónUna vez reconstituido: 2-8°C (nevera).

AdvertenciaHerramienta teórica para manipulación química. No constituye un consejo médico.

Abro la calculadora de dilución

Lo que es normal al recibirloLas observaciones que inquietan a los clientes y no son defectos

La cantidad de polvo parece mínima. Un liofilizado ocupa unos pocos milímetros en el fondo del vial, a veces solo una película translúcida. El peso indicado está ahí.
El polvo está compacto, pegado a la pared o al tapón. El transporte desplaza la torta liofilizada. No cambia nada en la reconstitución.
El vial no lleva etiqueta individual. Es nuestro embalaje estándar, no un vial de menor calidad.
Tras la reconstitución aparecen depósitos o filamentos. Es habitual, sobre todo con moléculas pequeñas. Deje que se asiente y haga rodar el vial entre las palmas, nunca lo agite.
El paquete es neutro. Nada en el exterior indica el contenido ni el nombre de la marca.

Lo que no es normal: un vial agrietado, una cápsula sin engastar o un tapón que se mueve, polvo que se ha licuado o cambiado de color. En esos casos concretos, escríbanos con una foto y recuperamos el vial.

Handling

04Conservación y manipulación

In lyophilized form, Thymosin Alpha-1 10mg is stored at -20°C, away from light, and remains stable for several months to several years. The dry powder tolerates a few days of room-temperature transport, but a quick return to the freezer on receipt is recommended for this polypeptide, longer than tetrapeptides.

After reconstitution, the solution must be kept at +2/+8°C (refrigerator) and used within a short period (a few weeks at most). Bacteriostatic water (0.9% benzyl alcohol) allows multiple draws from the same vial, matching the serial use of the 10mg format. Absolutely avoid freeze/thaw cycles of the solution, which degrade peptide integrity.

Each Atlas Lab batch is HPLC-tested at over 98% purity, vacuum lyophilized.

01What is the difference between Thymosin Alpha-1 and TB-500 (Thymosin Beta-4)?

These are two **totally different** peptides despite the shared name. **Thymosin Alpha-1** (28 amino acids) targets **immunity**: T lymphocyte maturation, dendritic cells, Th1/Th2 balance. **TB-500 / Beta-4** (43 amino acids) targets **tissue repair and cell migration** (actin, angiogenesis). Do not confuse them in a protocol.

02Why the 10mg format over the 5mg?

The **10mg** doubles the material: a single batch covers a complete series of long or fractionated-dose protocols, with homogeneous material and a better cost per milligram. The 5mg remains suited to a short or one-off test.

03How much water to reconstitute the 10mg vial?

**2 ml of bacteriostatic water** yields 5 mg/ml; **1 ml** yields 10 mg/ml for a small draw volume. Reconstitute gently without vortexing, draw under aseptic conditions, keep cold after reconstitution (long, more sensitive peptide).

04Is Thymosin Alpha-1 an approved drug?

The molecule (thymalfasin, Zadaxin) is **approved as a drug in over thirty countries** for certain indications (viral hepatitis, immune adjuvant). However, the Thymosin Alpha-1 sold by Atlas Lab is a **research reagent (RUO)**, without therapeutic status, intended only for in vitro and model studies.

05How does Thymosin Alpha-1 act on the immune system?

It activates the **TLR-2 and TLR-9** receptors of dendritic cells, orients T lymphocytes toward the **Th1** profile (IL-2 and interferon gamma production), stimulates T lymphocyte maturation and increases NK cell activity. Its hallmark is to **rebalance** a dysregulated immune system rather than over-stimulate it.

06How to store Thymosin Alpha-1?

Lyophilized: **-20°C away from light**. Reconstituted: **+2/+8°C**, to use within a few weeks, **without freeze/thaw cycles**. This 28 amino acid polypeptide is more sensitive than short peptides: a quick return to the freezer on receipt is advised.

Benchmark

Péptidos similares

Thymosin Alpha-1 10mg vs 5mg. Same molecule, same purity. The 5mg suffices for a short test. The 10mg is the reinforced format for long or fractionated-dose protocols: a single batch covers a complete series, ensuring material homogeneity and a better cost per milligram. For sustained immunological research, the 10mg is the obvious choice.

Thymosin Alpha-1 vs Thymosin Beta-4 (TB-500). Frequent confusion, very different molecules. Talpha1 is a 28 amino acid thymic peptide targeting immunity (T lymphocyte maturation, dendritic cells). Beta-4 / TB-500 is a 43 amino acid peptide targeting cell migration and tissue repair (actin, angiogenesis). Opposite biological targets despite the shared name.

Thymosin Alpha-1 vs other peptide immunomodulators. Compared with single-action immunostimulants, Talpha1 stands out for its bidirectional modulation: it rebalances rather than over-activates, a rare and documented property that explains its extensive clinical corpus.

Thymosin Alpha-1 vs LL-37 / KPV. LL-37 and KPV target antimicrobial immunity and local inflammation more; Talpha1 acts upstream on T lymphocyte maturation and orientation. Complementary in a global immune approach.

Thymosin Alpha-1 10mg Inmunidad y Salud

Inmunidad

01
Mecanismo de acción

02Estudios clínicos

03
Protocolos de investigación

Asepsia

Disolvente

Introducción

Solubilización

04Conservación y manipulación

Péptidos similares

Inmunidad

Información del producto

Asepsia

Disolvente

Introducción

Solubilización

Reactivos complementarios